Friday, May 27, 2016

Colistin Resistant Superbug

WaPo: The superbug that doctors have been dreading just reached the U.S.
The antibiotic-resistant strain was found last month in the urine of a 49-year-old Pennsylvania woman.

It’s the first time this colistin-resistant strain has been found in a person in the United States.
From Wikipedia -
Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity (poisonous effect on the kidneys). It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter.[1] NDM-1 metallo-β-lactamase multidrug-resistant Enterobacteriaceae have also shown susceptibility to colistin.[2] Resistance to colistin has been identified in the Escherichia coli strain SHP45, carried by the mcr-1 gene.[3]

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