Leprosy

Early American settlers somehow spread the bacteria that causes leprosy to armadillos. Well they can give it right on back.

Live Science: Leprosy Jumps from U.S. Armadillos to Humans

"People hunt them, eat them, make souvenirs out of their shell...Eating or handling raw or improperly cooked meat should be avoided, as it may have enormous number of bacteria if that armadillo had leprosy."